General Western Blot Reagents
Abcam Pro-myristic acid, Negative control for MiTMAB™ and OcTMAB™, 5MG
MW 299.5 Da. Negative control molecule for use with MiTMAB™ ab120466 and OcTMAB™ ab120467. Pro-myristic acid is an *in vitro* inhibitor of dynamin I and II, targeting the PH (lipid binding) domain (IC50 = 9.2 µM for inhibition of dynamin I GTPase). Although cell-permeable, it is rapidly broken down by cellular esterases to release intracellular myristic acid, which is not a dynamin inhibitor (IC50 = ≥300 μM for receptor-mediated endocytosis). It can therefore be used as a negative control in cell-based studies with MiTMAB™ and/or OcTMAB™.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Erythromycin, Macrolide antibiotic, 5G
MW 733.9 Da. Macrolide antibiotic. Inhibits cytochrome p450 3A4 and P-glycoprotein. Binds the 50S ribosomal subunit and inhibits protein synthesis in Gram-positive and Gram-negative bacteria.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AM 80, retinoic acid receptor alpha/beta (RAR alpha/beta) agonist, 50MG
MW 351.44 g/mol, Purity >98%. Selective retinoic acid receptor α/β (RARα/β) agonist. Induces differentiation and anti-cancer activity in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Phortress, Antitumor agent, 50MG
MW 459.4 Da, Purity >98%. Potent antitumor agent (IC₅₀ values for MCF-7 and MDA468 cells are 40 nM and 158 nM, respectively). Active against breast, ovarian and renal carcinomas. Taken up into sensitive cells followed by aryl hydrocarbon receptor binding and translocation into the nucleus. Requires metabolic activation by cytochrome P450 to generate cytotoxic species. Active in vitro and in vivo. Water soluble.
The product is subject to the following: Abcam Restricted Use Statement
Abcam NBQ x disodium salt (mM/ml), AMPA / kainate antagonist, 50MM_ML
MW 380.25 Da, Purity >98%. Water soluble, potent, selective and competitive AMPA/kainate receptor antagonist. Neuroprotective and anticonvulsant in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Doceta x el, Cytoto x ic agent, 50MG
MW 807.9 Da, Purity >99%. Potent cytotoxic agent in vitro (IC₅₀ = 2 nM). Disrupts microtubule assembly and arrests cell divison at G₂/M phase. Induces apoptosis. Antitumor agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Nifedipine, L-type Ca2+ channel blocker, 250MG
MW 346.3 Da, Purity >99%. L-type Ca2+ channel blocker. Potent, long-acting vasodilator. Also shown to inhibit vascular inflammation.
The product is subject to the following: Abcam Restricted Use Statement
Abcam rac-alpha-Tocopherol (alpha-Tocopherol), Vitamin E form, 1ML
MW 430.7 Da, Purity >95%. Fat-soluble antioxidant. Peroxyl radical scavenger that protects polyunsaturated fatty acids in membranes and lipoproteins. Anticarcinogen.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Indo-1 AM, fluorescent Ca2+ indicator, 1MG
MW 1009.9 Da, Purity >95%. Cell-permeable, ratiometric, fluorescent Ca2+ indicator. Binds to Ca2+ with high affinity (Kd = 230 nM). Fluoresces blue/violet and fluorescence increases upon Ca2+ binding. Cell-impermeable form, Indo 1 K+ salt (ab142779) also available. Emission and excitation shifts from 475 to 401 nm and 346 to 330 nm respectively depending on Ca2+ binding.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 5,7-Dichlorokynurenic acid sodium salt (mM/ml), NMDA receptor glycine site antagonist, 10MM_ML
MW 280.04 Da, Purity >99%. Potent NMDA receptor glycine site antagonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 680C91, tryptophan 2,3-dio x ygenase inhibitor, 5MG
MW 238.26 Da. Potent, selective, substrate competitive tryptophan 2,3-dioxygenase inhibitor (Ki = 51 nM). Inhibits tryptophan catabolism. Increases brain tryptophan and serotonin levels in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam ANA-12, TrkB antagonist, 25MG
MW 407.49 g/mol. ANA-12, TrkB antagonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Bufalin, Na+/K+-ATPase inhibitor, 10MG
MW 386.5 Da, Purity >98%. Na+/K+-ATPase inhibitor. Potent steroid receptor coactivators SRC-3 and SRC-1 inhibitor. Induces cell differentiation and apoptosis. Activates AP-1 via JNK. Shows antitumor effects *in vivo.*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human Histone H3 (tri methyl K9) peptide, 1MG
Human Histone H3 (tri methyl K9) peptide is a Synthetic blocking peptide. >90% purity and suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: H3FA, HIST1H3A, H3C2, H3FL, HIST1H3B, H3C3, H3FC HIST1H3C, H3C4, H3FB, HIST1H3D, H3C6, H3FD, HIST1H3E, H3C7, H3FI, HIST1H3F, H3C8, H3FH, HIST1H3G, H3C10, H3FK, HIST1H3H, H3C11, H3FF, HIST1H3I, H3C12, H3FJ, HIST1H3J, H3C1, H3FC, HIST1H3C, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, H3K9me3
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam Fast green FCF, tissue and protein stain, 25G
MW 808.86 g/mol. Widely utilized tissue and protein stain. Used as a quantitative stain for histones at alkaline pH after acid extraction of DNA and as a protein stain in IEF (isoelectric focusing) and SDS-PAGE electrophoresis. Fluoresces in the near-infrared (NIR). Recommended as a replacement for Light Green SF yellowish in Masson's trichrome as its color is more brilliant and less likely to fade. Also used as a food dye.
The product is subject to the following: Abcam Restricted Use Statement